Global Tractography of Multi-shell Hardi Data
نویسندگان
چکیده
PURPOSE – Conventional fibre tracking techniques estimate the fibre directions in all voxels and then use a local stepping method to track the entire pathway. However, the sensitivity of these techniques to local estimation errors is a well-known issue, as well as ambiguous fibre configurations arising from the symmetry of the DWI data [1,2]. Global fibre tracking methods [2–5], on the other hand, aim to reconstruct the full track configuration that best explains the data as a whole. Current methods have been limited to single-shell HARDI data and use fixed models for the fibre response function. In this study, we extend the method of Reisert et al. [3] for multi-shell HARDI data and allow to use arbitrary fibre response functions, estimated from the data.
منابع مشابه
Multi-subject Diffusion Mri Tractography via a Hough Transform Global Approach
Introduction: Multi-subject tractography in Diffusion-Weighted MRI is a valuable technique for statistical analysis of the brain‟s anatomical connectivity and population studies (e.g., Leemans et al. 2006; Voineskos et al. 2008; Jbabdi et al. 2009). Prior approaches are based on the post processing of tractography results from individual subjects, and generally require aligning the tracts and m...
متن کاملMicroTrack: An Algorithm for Concurrent Projectome and Microstructure Estimation
This paper presents MicroTrack, an algorithm that combines global tractography and direct microstructure estimation using diffusion-weighted imaging data. Previous work recovers connectivity via tractography independently from estimating microstructure features, such as axon diameter distribution and density. However, the two estimates have great potential to inform one another given the common...
متن کاملConverting Multi-Shell and Diffusion Spectrum Imaging to High Angular Resolution Diffusion Imaging
Multi-shell and diffusion spectrum imaging (DSI) are becoming increasingly popular methods of acquiring diffusion MRI data in a research context. However, single-shell acquisitions, such as diffusion tensor imaging (DTI) and high angular resolution diffusion imaging (HARDI), still remain the most common acquisition schemes in practice. Here we tested whether multi-shell and DSI data have conver...
متن کامل7T multi-shell hybrid diffusion imaging (HYDI) for mapping brain connectivity in mice
Diffusion weighted imaging (DWI) is widely used to study microstructural characteristics of the brain. High angular resolution diffusion imaging (HARDI) samples diffusivity at a large number of spherical angles, to better resolve neural fibers that mix or cross. Here, we implemented a framework for advanced mathematical analysis of mouse 5-shell HARDI (b=1000, 3000, 4000, 8000, 12000 s/mm2), al...
متن کاملMulti-Fascicle Model Reconstruction from Acquisitions at a Single b-value with a Population-Informed Prior
Purpose. Diffusion tensor images (DTI) have been widely used to characterize the white matter microstructure. The incapacity of DTI to represent crossing pathways has motivated the developement of novel diffusion models, such as the multi-tensor models. However, to estimate a multi-tensor model, one needs to acquire the diffusion weighted images (DWI) at multiple b-values, unlike the common sin...
متن کامل